Highly Hazardous Pesticides (HHPs) constitute a relatively small group of pesticides that, among all pesticides, have disproportionately negative impacts on human and environmental health, largely due to their high toxicity. HHPs have been linked to severe acute and chronic poisoning, particularly in Lower and Middle-Income Countries (LMICs).

In response to global recognition of the harms caused by HHPs, a number of binding and non-binding international agreements have set targets to dramatically reduce the risks from HHPs, including phasing-out HHP products where possible and upscaling alternatives to these harmful chemicals.